Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907110 | 0.91 | XPO1 (0.44) | XPO1ALDH1A1TDP1LMNAMAPT | |
| SCHEMBL2346544 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TDP1RAB9AHSD17B10HPGD | |
| SCHEMBL2346553 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TDP1RAB9AHSD17B10HPGD | |
| SCHEMBL28674986 | 0.87 | HSD17B10 (0.36) | ALDH1A1TDP1RAB9AHSD17B10GAA | |
| SCHEMBL28674985 | 0.87 | HSD17B10 (0.36) | ALDH1A1TDP1RAB9AHSD17B10GAA | |
| SCHEMBL2584512 | 0.87 | TRPM8 (0.46) | ALDH1A1TDP1RAB9AHSD17B10HPGD | |
| SCHEMBL22040222 | 0.86 | NR3C2 (0.43) | ALDH1A1TDP1RAB9AHSD17B10HPGD | |
| SCHEMBL2344446 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRLMNAKDM4E | |
| SCHEMBL2344442 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRLMNAKDM4E | |
| SCHEMBL15832431 | 0.83 | ALDH1A1 (0.38) | ALDH1A1RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |