SCHEMBL25833132

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25833424	0.84	TGFBR1 (0.38)	TGFBR1TGFBR2ADORA2AADORA1ABL1
	SCHEMBL25380379	0.83	CYP11B1 (0.41)	TGFBR1TGFBR2ADORA2AADORA1ABL1
	SCHEMBL30510017	0.83	CYP11B1 (0.41)	TGFBR1TGFBR2ADORA2AADORA1ABL1
	SCHEMBL25833010	0.83	SCN4A (0.45)	TGFBR1CHEK1ADORA2AGRIN2BCYP11B2
	SCHEMBL26193069	0.80	TGFBR1 (0.37)	TGFBR1TGFBR2CHEK1GRIN2BCYP11B2
	SCHEMBL1553745	0.75	SCN4A (0.46)	TGFBR1CYP11B2CYP11B1ALDH1A1AR
	SCHEMBL30510090	0.72	CDK7 (0.42)	TGFBR1GRIN2B
	SCHEMBL25379650	0.72	CDK7 (0.42)	TGFBR1GRIN2B
	SCHEMBL25833063	0.72	ERBB2 (0.41)	CHEK1CYP11B2CYP11B1ALDH1A1CYP1A2
	SCHEMBL30509969	0.71	GRIN1 (0.41)	GRIN2BCYP11B2CYP11B1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.