Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20221254 | 0.90 | PDE10A (0.47) | PDE10ASCN10ASCN5A | |
| SCHEMBL17790219 | 0.83 | PDE10A (0.60) | PDE10A | |
| SCHEMBL19390585 | 0.83 | PDE10A (0.49) | PDE10ASCN10ASCN5AALDH1A1MAPT | |
| SCHEMBL2163489 | 0.76 | BACE1 (0.44) | PDE10ASSTR3CCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL28446503 | 0.75 | SCN10A (0.44) | PDE10ASCN10ASCN5A | |
| SCHEMBL5756074 | 0.73 | SCN2A (0.49) | PDE10ASSTR3SCN10ACCNB2CDK1 | |
| SCHEMBL8221175 | 0.73 | MASP2 (0.66) | PDE10ACCNB2CDK1CCNB1GSK3A | |
| SCHEMBL7483325 | 0.73 | CYP2A6 (0.53) | PDE10ASSTR3CCNB2CDK1CCNB1 | |
| SCHEMBL17516278 | 0.72 | ALDH1A1 (0.42) | PDE10ASSTR3CCNB2CDK1CCNB1 | |
| SCHEMBL19789920 | 0.72 | SSTR3 (0.42) | PDE10ASSTR3SCN10ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135057-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-07-20 | — | — | WO | disclosed |