Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CDA | P32320 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13026809 | 0.88 | LMNA (0.72) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18720728 | 0.88 | LMNA (0.72) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18512923 | 0.88 | LMNA (0.72) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14418619 | 0.88 | LMNA (0.57) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18503539 | 0.88 | LMNA (0.72) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL16229237 | 0.88 | LMNA (0.72) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL9465323 | 0.84 | LMNA (0.79) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14577673 | 0.84 | LMNA (0.79) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL9465332 | 0.84 | LMNA (0.79) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18503527 | 0.79 | LMNA (0.56) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | CD4, CRBN, GZMB | LMNA 3945/4885MTOR 3750/4885THRB 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.