Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370837 | 0.84 | CRBN (0.51) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL411456 | 0.70 | CRBN (0.71) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL17532444 | 0.68 | ALDH1A1 (0.54) | L3MBTL1TDP1ALDH1A1PPM1BKDM4E | |
| SCHEMBL12410834 | 0.68 | CRBN (0.51) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL29330443 | 0.67 | CRBN (0.56) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL20317524 | 0.67 | CRBN (0.61) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL17532446 | 0.66 | SMN1; SMN2 (0.46) | L3MBTL1TDP1ALDH1A1PPM1BKDM4E | |
| SCHEMBL17277068 | 0.66 | CRBN (0.76) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL6508946 | 0.66 | PPM1B (0.47) | L3MBTL1TDP1PPM1BKDM4EGMNN | |
| SCHEMBL17246852 | 0.65 | CRBN (0.77) | CRBNDDB1TDP1IKZF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | CD4, CRBN, GZMB | L3MBTL1 3391/4885CRBN 2/4885DDB1 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.