Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2348006 | 0.82 | DPP4 (0.40) | DPP4RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL2348001 | 0.82 | DPP4 (0.40) | DPP4RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL4501380 | 0.81 | TRPA1 (0.37) | DPP4RIPK1TRPA1ATM | |
| SCHEMBL14563128 | 0.81 | TRPA1 (0.47) | TRPA1ABCB1TACR1 | |
| SCHEMBL14563127 | 0.81 | TRPA1 (0.47) | TRPA1ABCB1TACR1 | |
| SCHEMBL2350570 | 0.81 | TRPA1 (0.47) | TRPA1ABCB1TACR1 | |
| SCHEMBL2351859 | 0.81 | FFAR2 (0.43) | DPP4TRPA1GPR119ABCB1TACR1 | |
| SCHEMBL28528295 | 0.80 | RIPK1 (0.50) | RIPK1TRPA1GPR119ABCB1 | |
| SCHEMBL24293065 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1CHRM3SMN1; SMN2NR1H2 | |
| SCHEMBL31433028 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1CHRM3SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |