SCHEMBL25834927

SCHEMBL25834927

CSCC(=O)Nc1cccc(C(=O)NCCNC(=O)CCCc2ccc(C)cc2)c1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
POLB P06746 1/20 0.49
BACE1 P56817 2/20 0.47
KDM1A O60341 2/20 0.47
ALDH1A1 P00352 1/20 0.45
MAOA P21397 1/20 0.44
LMNA P02545 1/20 0.44
HDAC6 Q9UBN7 1/20 0.42
RECQL P46063 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PAX8 Q06710 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25841130 0.92 RAB9A (0.54) GAANPC1RAB9APOLBBACE1
SCHEMBL25834932 0.90 KDM1A (0.57) GAANPC1RAB9ABACE1KDM1A
SCHEMBL25841132 0.86 GAA (0.45) GAANPC1RAB9APOLBBACE1
SCHEMBL25841169 0.81 LMNA (0.65) NPC1RAB9ABACE1ALDH1A1LMNA
SCHEMBL25840295 0.78 NPC1 (0.54) GAANPC1RAB9APOLBALDH1A1
SCHEMBL23573699 0.74 KDM1A (0.59) GAANPC1RAB9ABACE1KDM1A
SCHEMBL23573700 0.74 KDM1A (0.61) GAANPC1RAB9ABACE1KDM1A
SCHEMBL12092129 0.73 KMT2A (0.53) GAANPC1RAB9APOLBALDH1A1
SCHEMBL25834928 0.70 POLB (0.52) POLBALDH1A1LMNAHDAC6
SCHEMBL14033071 0.70 RECQL (0.68) POLBALDH1A1HDAC6RECQLL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287170-A1 FLUORESCENT DYES COMPRISING M-CONJUGATED 1,1 -BINAPHTHYL-BASED POLYMERS Miltenyi Biotec B.V. & Co. KG (DE) 2023-09-14 US disclosed
US-20230228746-A1 Water-soluble M-conjugated fluorescent 1,1-binaphthyl-based tandem polymers Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-20 US disclosed
US-20230228746-A1 Water-soluble M-conjugated fluorescent 1,1-binaphthyl-based tandem polymers Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-20 US disclosed
US-20230228745-A1 WATER-SOLUBLE II-CONJUGATED FLUORESCENT 1,1 -BINAPHTHYL-BASED POLYMERS WITH TUNEABLE ABSORPTION Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-20 US disclosed
EP-4212593-A1 WATER-SOLUBLE PI-CONJUGATED FLUORESCENT 1,1´-BINAPHTHYL-BASED POLYMERS WITH TUNEABLE ABSORPTION Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-19 EP disclosed