SCHEMBL25834932

SCHEMBL25834932

CSCC(=O)Nc1cccc(C(=O)NCCc2ccc(C)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.57
BACE1 P56817 2/20 0.56
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
GAA P10253 2/20 0.54
LMNA P02545 1/20 0.54
MAOA P21397 1/20 0.53
MAPT P10636 3/20 0.48
KMT2A Q03164 3/20 0.48
RECQL P46063 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25841169 0.91 LMNA (0.65) BACE1NPC1RAB9ALMNAMAPT
SCHEMBL25834927 0.90 GAA (0.51) KDM1ABACE1NPC1RAB9AGAA
SCHEMBL25841132 0.85 GAA (0.45) KDM1ABACE1NPC1RAB9AGAA
SCHEMBL23573700 0.83 KDM1A (0.61) KDM1ABACE1NPC1RAB9AGAA
SCHEMBL23573699 0.81 KDM1A (0.59) KDM1ABACE1NPC1RAB9AGAA
SCHEMBL25841130 0.81 RAB9A (0.54) BACE1NPC1RAB9AGAALMNA
SCHEMBL12092129 0.78 KMT2A (0.53) NPC1RAB9AGAALMNAMAPT
SCHEMBL31424939 0.76 HDAC8 (0.76) KDM1ANPC1RAB9ALMNAMAOA
SCHEMBL8392950 0.76 KDM1A (0.53) KDM1ABACE1NPC1RAB9ALMNA
SCHEMBL19472777 0.76 KMT2A (0.79) NPC1RAB9AGAALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287170-A1 FLUORESCENT DYES COMPRISING M-CONJUGATED 1,1 -BINAPHTHYL-BASED POLYMERS Miltenyi Biotec B.V. & Co. KG (DE) 2023-09-14 US disclosed
US-20230228746-A1 Water-soluble M-conjugated fluorescent 1,1-binaphthyl-based tandem polymers Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-20 US disclosed
US-20230228746-A1 Water-soluble M-conjugated fluorescent 1,1-binaphthyl-based tandem polymers Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-20 US disclosed
US-20230228745-A1 WATER-SOLUBLE II-CONJUGATED FLUORESCENT 1,1 -BINAPHTHYL-BASED POLYMERS WITH TUNEABLE ABSORPTION Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-20 US disclosed
EP-4212594-A1 WATER-SOLUBLE -CONJUGATED FLUORESCENT 1,1' -BINAPHTHYL-BASED TANDEM POLYMERS Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-19 EP disclosed
EP-4212593-A1 WATER-SOLUBLE PI-CONJUGATED FLUORESCENT 1,1´-BINAPHTHYL-BASED POLYMERS WITH TUNEABLE ABSORPTION Miltenyi Biotec B.V. & Co. KG (DE) 2023-07-19 EP disclosed