Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835284 | 0.86 | CDK4 (0.47) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL14933432 | 0.83 | PARP1 (0.62) | TNKS2PARP1MMP2MMP9MMP8 | |
| SCHEMBL25835160 | 0.82 | AHR (0.67) | TNKS2PARP1AHRSRCKDM4E | |
| SCHEMBL149685 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL12001022 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL29386403 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL30300831 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL17154708 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL19041639 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 | |
| SCHEMBL3365890 | 0.81 | CDK4 (0.57) | TNKS2CDK4CCND1AHRFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110742-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |