SCHEMBL25835443

SCHEMBL25835443

CC/C=C\CCCC(=O)NCCOCCNC(=O)OC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 8/20 0.52
▸ LPAR1 Q92633 2/20 0.43
▸ LPAR2 Q9HBW0 2/20 0.43
▸ ENPP2 Q13822 1/20 0.43
▸ MAPT P10636 2/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ FAAH O00519 2/20 0.42
▸ CNR2 P34972 2/20 0.42
▸ TRPM8 Q7Z2W7 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KCNK3 O14649 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ TRPV1 Q8NER1 1/20 0.42
▸ EPHX2 P34913 1/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ HPGD P15428 1/20 0.41
▸ ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15700831 0.88 CNR1 (0.64) CNR1MAPTALDH1A1FAAHCNR2
SCHEMBL29744529 0.88 CNR1 (0.56) CNR1MAPTALDH1A1FAAHCNR2
SCHEMBL26032854 0.84 LPAR1 (0.56) CNR1LPAR1LPAR2ENPP2MAPT
SCHEMBL26032858 0.84 LPAR1 (0.56) CNR1LPAR1LPAR2ENPP2MAPT
SCHEMBL26032860 0.84 LPAR1 (0.56) CNR1LPAR1LPAR2ENPP2MAPT
SCHEMBL25835504 0.84 TDP1 (0.42) CNR2MEN1KMT2ATDP1
SCHEMBL31298557 0.84 TDP1 (0.47) CNR1FAAHMEN1KMT2ATDP1
SCHEMBL12722380 0.83 CNR1 (0.57) CNR1MAPTALDH1A1FAAHCNR2
SCHEMBL1604840 0.83 CNR1 (0.57) CNR1MAPTALDH1A1FAAHCNR2
SCHEMBL26032884 0.83 TDP1 (0.41) CNR2MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CNR1 4510/4885LPAR1 147/4885LPAR2 74/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 CNR1 4167/4885LPAR1 1841/4885LPAR2 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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