SCHEMBL26032860

SCHEMBL26032860

CCCCCCCC/C=C\CCCCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LPAR1 Q92633 3/20 0.56
▸ LPAR2 Q9HBW0 2/20 0.56
▸ ENPP2 Q13822 1/20 0.56
▸ EPHX2 P34913 2/20 0.52
▸ CNR1 P21554 3/20 0.52
▸ ALDH1A1 P00352 2/20 0.51
▸ HPGD P15428 2/20 0.51
▸ SLC6A5 Q9Y345 2/20 0.51
▸ TRPV1 Q8NER1 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ ALOX12 P18054 1/20 0.51
▸ BLM P54132 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032858 1.00 LPAR1 (0.56) LPAR1LPAR2ENPP2EPHX2CNR1
SCHEMBL26032854 1.00 LPAR1 (0.56) LPAR1LPAR2ENPP2EPHX2CNR1
SCHEMBL25067291 0.93 FAAH (0.47) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL25067424 0.93 FAAH (0.47) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL16582456 0.93 FAAH (0.47) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL25835309 0.92 FAAH (0.48) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL25835294 0.92 FAAH (0.48) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL23475914 0.91 FAAH (0.49) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL23475931 0.91 FAAH (0.49) LPAR1LPAR2ENPP2CNR1TDP1
SCHEMBL32680127 0.91 FAAH (0.49) LPAR1LPAR2ENPP2CNR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 LPAR1 1841/4885LPAR2 1529/4885ENPP2 1181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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