Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | TYK2 | P29597 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16680860 | 0.76 | HSP90AA1 (0.42) | TSHRALDH1A1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL30873890 | 0.68 | TLR8 (0.41) | CYP17A1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL22411322 | 0.68 | TLR8 (0.41) | CYP17A1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL2201444 | 0.68 | ADORA2A (0.41) | TSHRALDH1A1CDK2CCNA1FLT3 | |
| SCHEMBL30675628 | 0.65 | L3MBTL1 (0.38) | JAK2JAK3ALDH1A1GAAFLT3 | |
| SCHEMBL26675398 | 0.65 | L3MBTL1 (0.38) | JAK2JAK3ALDH1A1GAAFLT3 | |
| SCHEMBL14722578 | 0.64 | IGF1R (0.47) | CDK2CCNA1CCNA2 | |
| SCHEMBL25370864 | 0.64 | CA2 (0.40) | CYP17A1 | |
| SCHEMBL22252781 | 0.63 | IRAK4 (0.38) | NOTUMCDK2CCNA1FLT3HSP90AB1 | |
| SCHEMBL5024252 | 0.63 | HTR2C (0.44) | NOTUMIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023120452-A1 | SREBP-1 INHIBITOR AND PHARMACEUTICAL COMPOSITION FOR TREATING HYPERTRIGLYCERIDEMIA | 国立大学法人筑波大学 | 2023-06-29 | — | — | WO | disclosed |