SCHEMBL25835683

SCHEMBL25835683

CCCCCCCCCCCCCCCC(=O)NCCOCCNC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.59
CAPN1 P07384 1/20 0.54
CTSK P43235 4/20 0.52
CTSS P25774 3/20 0.52
BCHE P06276 2/20 0.47
ACHE P22303 2/20 0.47
SIRT2 Q8IXJ6 2/20 0.44
LPAR3 Q9UBY5 3/20 0.42
LPAR1 Q92633 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032865 0.99 GLP1R (0.61) GLP1RCAPN1CTSKCTSSBCHE
SCHEMBL25835366 0.96 GLP1R (0.55) GLP1RCAPN1CTSKCTSSBCHE
SCHEMBL26032519 0.96 GLP1R (0.55) GLP1RCAPN1CTSKCTSSBCHE
SCHEMBL26032874 0.93 GLP1R (0.55) GLP1RCAPN1CTSKCTSSLPAR1
SCHEMBL16853275 0.92 GLP1R (0.58) GLP1RCAPN1CTSKCTSSSIRT2
SCHEMBL20341078 0.92 GLP1R (0.58) GLP1RCAPN1CTSKCTSSSIRT2
SCHEMBL25835480 0.91 CTSK (0.52) GLP1RCAPN1CTSKCTSSBCHE
SCHEMBL23475912 0.90 GLP1R (0.56) GLP1RCAPN1CTSKCTSSSIRT2
SCHEMBL16853476 0.90 GLP1R (0.56) GLP1RCAPN1CTSKCTSSSIRT2
SCHEMBL23475929 0.90 GLP1R (0.56) GLP1RCAPN1CTSKCTSSSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 GLP1R 1985/4885CAPN1 3157/4885CTSK 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.