SCHEMBL25835480

SCHEMBL25835480

CCCC(=O)NCCOCCNC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCOCCNC(=O)CCC

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.52
CTSS P25774 7/20 0.52
CAPN1 P07384 1/20 0.52
GLP1R P43220 8/20 0.48
BCHE P06276 2/20 0.47
ACHE P22303 2/20 0.47
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032522 0.98 CTSK (0.50) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL25835366 0.92 GLP1R (0.55) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL25835683 0.91 GLP1R (0.59) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL26032865 0.90 GLP1R (0.61) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL26046247 0.89 CTSK (0.58) CTSKCTSSCAPN1BCHEACHE
SCHEMBL30842626 0.88 GLP1R (0.48) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL26032519 0.87 GLP1R (0.55) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL25835493 0.87 CAPN1 (0.50) CTSKCTSSCAPN1GLP1RBCHE
SCHEMBL26032874 0.84 GLP1R (0.55) CTSKCTSSCAPN1GLP1R
SCHEMBL23895013 0.84 CAPN1 (0.59) CTSKCTSSCAPN1GLP1RBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CTSK 2527/4885CTSS 3695/4885CAPN1 3157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.