SCHEMBL25835868

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25835864	0.84	TDP1 (0.38)	L3MBTL1KDM4ETSHRMAPK1ALDH1A1
	SCHEMBL25835993	0.77	TUBB4A (0.42)	L3MBTL1KDM4EALOX15TSHRALDH1A1
	SCHEMBL25835874	0.77	NPSR1 (0.38)	L3MBTL1KDM4EALOX15TSHRMAPK1
	SCHEMBL25836116	0.76	F2 (0.40)	L3MBTL1KDM4EALOX15TSHRALDH1A1
	SCHEMBL23975974	0.74	KMT2A (0.40)	L3MBTL1ALDH1A1TDP1RXRAGRIN1
	SCHEMBL30430043	0.74	MAPK1 (0.43)	ALOX15TSHRMAPK1ALDH1A1SMN1; SMN2
	SCHEMBL25836001	0.71	CACNA2D1 (0.39)	TSHRSMN1; SMN2LMNANPSR1EP300
	SCHEMBL11379919	0.70	ESR1 (0.43)	KDM4EALOX15TSHRMAPK1ALDH1A1
	Hydrochloric Acid SCHEMBL11378680	0.70	ALDH1A1 (0.47)	ALOX15TSHRMAPK1ALDH1A1GAA
	SCHEMBL25836039	0.67	TUBB4A (0.40)	L3MBTL1KDM4EALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.