Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834424 | 0.85 | HCAR3 (0.57) | GRM5HCAR3 | |
| SCHEMBL25834884 | 0.84 | HCAR3 (0.58) | GRM5HCAR3HPGDALDH1A1KDM4E | |
| SCHEMBL25533268 | 0.81 | GRM5 (0.64) | GRM5HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL30398095 | 0.81 | GRM5 (0.64) | GRM5HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL24100564 | 0.79 | GRM5 (0.63) | GRM5HCAR3HPGDALDH1A1KDM4E | |
| SCHEMBL990874 | 0.78 | GRM5 (1.00) | GRM5HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22086829 | 0.77 | VNN1 (0.65) | GRM5HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL1542481 | 0.77 | HCAR3 (1.00) | HCAR3 | |
| SCHEMBL28236426 | 0.77 | CDK2 (0.51) | GRM5HPGDL3MBTL3L3MBTL1CCNE1 | |
| SCHEMBL8115278 | 0.76 | HCAR3 (0.97) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |