Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.49 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603785 | 0.85 | PDGFRB (0.49) | PDGFRBPDGFRAACACBACACA | |
| SCHEMBL941428 | 0.84 | TDO2 (0.46) | HRH3 | |
| Hydrochloric Acid SCHEMBL20138397 | 0.83 | TDP1 (0.48) | HRH3 | |
| SCHEMBL20158603 | 0.83 | TDO2 (0.48) | RETMCHR1HRH3LIPE | |
| SCHEMBL624331 | 0.82 | LOX (0.40) | PDGFRBPDGFRAACACBLOXLOXL2 | |
| SCHEMBL20069585 | 0.80 | HRH3 (0.55) | HRH3 | |
| SCHEMBL15147591 | 0.79 | PDGFRB (0.44) | PDGFRBPDGFRAACACBLOXLOXL2 | |
| SCHEMBL21525586 | 0.79 | DGAT1 (0.53) | — | |
| SCHEMBL19977842 | 0.79 | KDM1A (0.39) | KDM4ERETMCHR1LIPE | |
| SCHEMBL20147967 | 0.79 | MCHR1 (0.40) | ACACBRETMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | HOFFMANN-LA ROCHE INC. (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | AVPR1A, AVPR1B, AVPR2 | PDGFRB 1034/4885PDGFRA 728/4885ACACB 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.