Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924281 | 0.81 | MEN1 (0.48) | MAPK1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL692654 | 0.80 | HCAR3 (0.71) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL18571767 | 0.79 | PTGER4 (0.44) | MEN1KMT2AKDM4EPDE10APIM1 | |
| SCHEMBL22247518 | 0.77 | HCAR3 (0.70) | MAPK1HCAR3MEN1KMT2AKDM4E | |
| SCHEMBL13043454 | 0.77 | HCAR3 (0.57) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL3962368 | 0.76 | GPR39 (0.51) | MEN1KMT2AKDM4EPIM1 | |
| SCHEMBL24774175 | 0.75 | MAPK1 (0.51) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL6984008 | 0.75 | HCAR3 (0.68) | MAPK1HCAR3KMT2AKDM4EL3MBTL1 | |
| SCHEMBL24975204 | 0.75 | PTGER4 (0.47) | MAPK1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL20722658 | 0.74 | CA1 (0.62) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |