SCHEMBL25836308

SCHEMBL25836308

Cc1ccc2c(c1)Cc1c(SF)cccc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
METAP1 P53582 2/20 0.38
HSP90AA1 P07900 2/20 0.35
NPC1 O15118 2/20 0.34
PGR P06401 2/20 0.33
ACHE P22303 1/20 0.33
PDK2 Q15119 2/20 0.33
ELANE P08246 1/20 0.33
PNMT P11086 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
PARP10 Q53GL7 1/20 0.31
PARP11 Q9NR21 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24727268 0.79 PGR (0.50) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL29432302 0.78 MAPT (0.45) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL601330 0.78 MAPT (0.45) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL25720270 0.78 KDM4E (0.40) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL21730834 0.76 MAPT (0.43) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL4897556 0.71 METAP1 (0.57) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL29633547 0.71 METAP1 (0.57) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL22539769 0.71 PGR (0.43) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL18261221 0.71 METAP1 (0.46) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL25878365 0.70 METAP1 (0.42) RAB9AMAPTKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136595-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME (주)피엔에이치테크 2023-07-20 WO disclosed