SCHEMBL29633547

SCHEMBL29633547

Cc1ccc2c(c1)Cc1cc(C)ccc1-2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.57
MAPT P10636 4/20 0.48
RAB9A P51151 3/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 2/20 0.46
PARP10 Q53GL7 2/20 0.45
PARP11 Q9NR21 1/20 0.45
ACHE P22303 1/20 0.42
HPGD P15428 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2A6 P11509 2/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897556 1.00 METAP1 (0.57) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL29332473 0.95 METAP1 (0.53) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL21694418 0.93 METAP1 (0.52) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL18568790 0.91 METAP1 (0.50) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL30634708 0.89 METAP1 (0.48) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL21498294 0.89 METAP1 (0.48) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL31400232 0.89 ALDH1A1 (0.59) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL1609497 0.89 ALDH1A1 (0.59) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL24727167 0.87 PGR (0.49) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL9973088 0.87 MAPT (0.62) METAP1MAPTRAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756967-A Silicon bridged metallocene catalyst and application thereof 上海化工研究院有限公司 2024-03-26 CN disclosed
CN-109824809-B Ethylene-alpha-olefin-nonconjugated polyene copolymer and use thereof 三井化学株式会社 2022-06-28 CN disclosed