SCHEMBL4897556

SCHEMBL4897556

Cc1ccc2c(c1)Cc1cc(C)ccc1-2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.57
MAPT P10636 4/20 0.48
RAB9A P51151 3/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 2/20 0.46
PARP10 Q53GL7 2/20 0.45
PARP11 Q9NR21 1/20 0.45
ACHE P22303 1/20 0.42
HPGD P15428 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2A6 P11509 2/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633547 1.00 METAP1 (0.57) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL29332473 0.95 METAP1 (0.53) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL21694418 0.93 METAP1 (0.52) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL18568790 0.91 METAP1 (0.50) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL30634708 0.89 METAP1 (0.48) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL21498294 0.89 METAP1 (0.48) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL31400232 0.89 ALDH1A1 (0.59) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL1609497 0.89 ALDH1A1 (0.59) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL24727167 0.87 PGR (0.49) METAP1MAPTRAB9AKDM4EALDH1A1
SCHEMBL9973088 0.87 MAPT (0.62) METAP1MAPTRAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-04-02 US disclosed
WO-2024075643-A1 THERMOPLASTIC RESIN COMPOSITION AND OPTICAL MEMBER COMPRISING SAME 帝人株式会社 2024-04-11 WO disclosed
CN-117756967-A Silicon bridged metallocene catalyst and application thereof 上海化工研究院有限公司 2024-03-26 CN disclosed
US-11760819-B2 Ethylene α-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-11613595-B2 Ethylene alpha-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2023-03-28 US disclosed
US-20220388958-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-12-08 US disclosed
EP-4043500-A1 ETHYLENE·ALPHA-OLEFIN·NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF Mitsui Chemicals, Inc. (JP) 2022-08-17 EP disclosed
CN-109824809-B Ethylene-alpha-olefin-nonconjugated polyene copolymer and use thereof 三井化学株式会社 2022-06-28 CN disclosed
US-11312717-B2 Organic nano-grid, nano-polymer thereof and preparation method therefor NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS (CN) 2022-04-26 US disclosed
EP-3106480-B1 ETHYLENE/A-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, USE THEREFOR, AND MANUFACTURING METHOD THEREFOR MITSUI CHEMICALS INC (JP) 2022-04-06 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
US-5420320-A Method for preparing cyclopentadienyl-type ligands and metallocene compounds PHILLIPS PETROLEUM COMPANY (US) 1995-05-30 US disclosed
EP-0627440-A1 9-Substituted fluorenyl compounds and the preparation and use of metallocenes thereof PHILLIPS PETROLEUM COMPANY (US) 1994-12-07 EP disclosed
EP-0577581-A2 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1994-01-05 EP disclosed
EP-0531443-A4 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN 1993-04-21 EP disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
EP-0531443-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN NOVA PHARMACEUTICAL CORPORATION (US) 1993-03-17 EP disclosed
US-5079260-A Side effect reduction; fluorene derivatives NOVA PHARMACEUTICAL CORPORATION (US) 1992-01-07 US disclosed
WO-1991018596-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN WEITZBERG MOSHE (US) 1991-12-12 WO disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388958-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE CRY1, AP3D1, AHR METAP1 4122/4885MAPT 3816/4885RAB9A 1995/4885
US-11312717-B2 Organic nano-grid, nano-polymer thereof and preparation method therefor ITGB2, CD81, ITGAV METAP1 4865/4885MAPT 3845/4885RAB9A 4364/4885
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES DYRK1B, DYRK2, DYRK4 METAP1 2580/4885MAPT 1992/4885RAB9A 632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.