SCHEMBL25836507

SCHEMBL25836507

COC(OC)c1c(I)cc(I)c(O)c1I

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.39
TDP1 Q9NUW8 1/20 0.36
ALB P02768 1/20 0.33
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929990 0.77 TTR (0.44) TTRTDP1ALBMEN1LMNA
SCHEMBL22991560 0.75 TTR (0.42) TTRTDP1ALBMEN1LMNA
SCHEMBL22991645 0.71 TTR (0.42) TTRTDP1ALBMEN1LMNA
SCHEMBL69776 0.69 TTR (0.56) TTRTDP1ALBMEN1LMNA
SCHEMBL25836509 0.69 APP (0.30)
SCHEMBL25836512 0.68 TTR (0.34) TTR
SCHEMBL25836502 0.68 TTR (0.56) TTRALBMEN1LMNAHTT
SCHEMBL25836511 0.68 APP (0.30)
SCHEMBL12817414 0.65 TTR (0.50) TTRTDP1ALBMEN1LMNA
SCHEMBL7929422 0.64 TTR (0.50) TTRTDP1ALBMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702498-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702498-B2 Radiopaque polymers OXER1, NR5A1, AQP1 TTR 3572/4885TDP1 1343/4885ALB 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.