SCHEMBL7929422

SCHEMBL7929422

Cc1c(I)cc(I)c(O)c1I

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.50
ALB P02768 1/20 0.41
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPK14 Q16539 2/20 0.34
CHEK1 O14757 1/20 0.34
DAPK3 O43293 1/20 0.34
RET P07949 1/20 0.34
PDGFRB P09619 1/20 0.34
PIM1 P11309 1/20 0.34
PDGFRA P16234 1/20 0.34
KDR P35968 1/20 0.34
MAPK8 P45983 1/20 0.34
RPS6KA3 P51812 1/20 0.34
LIMK1 P53667 1/20 0.34
TYRO3 Q06418 1/20 0.34
LRRK2 Q5S007 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26225283 0.82 TTR (0.42) TTRALBMEN1LMNAHTT
SCHEMBL69776 0.80 TTR (0.56) TTRALBMEN1LMNAHTT
SCHEMBL12817414 0.75 TTR (0.50) TTRALBMEN1LMNAHTT
SCHEMBL2265262 0.75 TPMT (0.31) TTR
SCHEMBL22906148 0.73 ERN1 (0.52) MEN1LMNAHTTKMT2APIM1
SCHEMBL18281063 0.73 TP53 (0.45) TTRMEN1LMNAHTTKMT2A
SCHEMBL8410940 0.72 TTR (0.48) TTRALBMEN1LMNAHTT
SCHEMBL18895852 0.72 TTR (0.42) TTRALBMEN1LMNAHTT
SCHEMBL7134885 0.71 TTR (0.61) TTRALBMEN1LMNAHTT
SCHEMBL15901979 0.69 ALDH1A1 (0.45) TTRALBMEN1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355833-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2023-11-09 US disclosed
US-20230355833-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2023-11-09 US disclosed
US-11744916-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-09-05 US disclosed
US-11744916-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-09-05 US disclosed
US-11702498-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-07-18 US disclosed
US-11702498-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-07-18 US disclosed
US-20210277162-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2021-09-09 US disclosed
US-20210115171-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2021-04-22 US disclosed
US-20210015963-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD. (GB) 2021-01-21 US disclosed
EP-3221400-A2 HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND PROCESS OF MANUFACTURING THEREOF Ester Industries Limited (IN) 2017-09-27 EP disclosed
EP-2120095-A1 RESIST LOWER LAYER FILM FORMING COMPOSITION FOR ELECTRON LITHOGRAPHY Nissan Chemical Industries, Ltd. (JP) 2009-11-18 EP disclosed
US-7309560-B2 Composition for forming anti-reflective coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-12-18 US disclosed
US-7309560-B2 Composition for forming anti-reflective coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-12-18 US disclosed
US-20070190459-A1 Resist underlayer coating forming composition for mask blank, mask blank and mask HOYA CORPORATION (JP) 2007-08-16 US disclosed
US-20070190459-A1 Resist underlayer coating forming composition for mask blank, mask blank and mask HOYA CORPORATION (JP) 2007-08-16 US disclosed
EP-0707849-B1 USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS BOBEL246 S L (ES) 2001-12-19 EP disclosed
EP-0707849-A1 USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS BOBEL246 S.L. (ES) 1996-04-24 EP disclosed
US-5248432-A Flotation fluids for gyroscopes and accelerometers CHARLES STARK DRAPER LABORATORY, INC. (US) 1993-09-28 US disclosed
US-5177252-A High density flotation fluids and lubricants for inertial instruments THE CHARLES STARK DRAPER LABORATORY, INC. (US) 1993-01-05 US disclosed
US-4835304-A FLOTATION FLUIDS FOR INERTIAL INSTRUMENTS SUCH AS GYROSCOPESAD ACCELEROMETERS; HIGH VISCOSITY; HYDRAULIC FLUIDS CHARLES STARK DRAPER LABORATORY (US) 1989-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115171-A1 RADIOPAQUE POLYMERS C9, PARG, RAD50 TTR 2257/4885ALB 2388/4885MEN1 259/4885
US-11702498-B2 Radiopaque polymers OXER1, NR5A1, AQP1 TTR 3572/4885ALB 3797/4885MEN1 1334/4885
US-20230355833-A1 RADIOPAQUE POLYMERS TPO, PGLS, IQGAP1 TTR 435/4885ALB 2256/4885MEN1 246/4885
US-20210015963-A1 RADIOPAQUE POLYMERS TPO, PGLS, IQGAP1 TTR 435/4885ALB 2256/4885MEN1 246/4885
US-11744916-B2 Radiopaque polymers TPO, PGLS, IQGAP1 TTR 435/4885ALB 2256/4885MEN1 246/4885
US-20210277162-A1 RADIOPAQUE POLYMERS OXER1, NR5A1, AQP1 TTR 3641/4885ALB 3804/4885MEN1 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.