Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836962 | 0.78 | HPGD (0.46) | RAB9ASMN1; SMN2HPGDMCHR1EPHX1 | |
| SCHEMBL4981117 | 0.78 | ACKR3 (0.54) | RAB9AMCHR1ALDH1A1 | |
| SCHEMBL13104293 | 0.77 | SETDB1 (0.56) | RAB9AHPGDNPC1 | |
| SCHEMBL879004 | 0.77 | PABPC1 (0.42) | MEN1KMT2AHTT | |
| SCHEMBL26156272 | 0.76 | SMN1; SMN2 (0.85) | RAB9ASMN1; SMN2HPGDMCHR1EPHX1 | |
| SCHEMBL25834182 | 0.76 | PDE4A (0.43) | RAB9ASMN1; SMN2HPGDMCHR1EPHX1 | |
| SCHEMBL25834549 | 0.75 | P2RX7 (0.52) | HPGDEPHX1PPIAHTT | |
| SCHEMBL10202757 | 0.75 | HPGD (0.45) | RAB9ASMN1; SMN2HPGDNPC1MAPT | |
| SCHEMBL3756353 | 0.74 | NPC1 (0.40) | RAB9AHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL29339265 | 0.74 | CARM1 (0.45) | RAB9AKMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |