Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834182 | 0.81 | PDE4A (0.43) | HPGDKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL25836749 | 0.78 | RAB9A (0.53) | HPGDKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27423311 | 0.77 | P2RX7 (0.39) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27003483 | 0.73 | LMNA (0.42) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25834549 | 0.73 | P2RX7 (0.52) | HPGDHTTEPHX1 | |
| SCHEMBL31593893 | 0.69 | SLC6A4 (0.39) | — | |
| SCHEMBL27428314 | 0.69 | SLC6A4 (0.39) | — | |
| SCHEMBL4980687 | 0.68 | HPGD (0.52) | HPGDKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL4981117 | 0.68 | ACKR3 (0.54) | ALDH1A1RAB9ATSHREPHX2MCHR1 | |
| SCHEMBL27423559 | 0.68 | P2RX7 (0.53) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |