Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836778 | 0.93 | TDO2 (0.36) | CYP1A1CYP1B1GAADUSP3AKR1C3 | |
| SCHEMBL25875887 | 0.89 | KCNH2 (0.35) | KCNH2KDM4EKMT2ACYP1A1CYP1B1 | |
| SCHEMBL25837296 | 0.83 | PDK2 (0.35) | KMT2AMAPTGAAMEN1HPGD | |
| SCHEMBL25875873 | 0.83 | IDO1 (0.36) | CYP1A1CYP1B1GAADUSP3AKR1C3 | |
| SCHEMBL25836787 | 0.82 | ALK (0.34) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL1815597 | 0.82 | KCNH2 (0.36) | KCNH2KDM4EKMT2ACYP1A1CYP1B1 | |
| SCHEMBL25875884 | 0.75 | ALK (0.35) | — | |
| SCHEMBL1816876 | 0.75 | IDO1 (0.39) | KDM4ECYP1A1CYP1B1MAPTGAA | |
| SCHEMBL25837171 | 0.75 | PDK2 (0.30) | — | |
| SCHEMBL30658970 | 0.74 | GSK3B (0.32) | KDM4EKMT2AHTTMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |