Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GGT1 | P19440 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836923 | 0.83 | PTGS2 (0.59) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL13537374 | 0.80 | PTGS2 (0.56) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL21916241 | 0.79 | PTGS2 (0.54) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3855465 | 0.77 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL27780055 | 0.76 | NPC1 (0.53) | HPGDALDH1A1TDP1CYP1A2 | |
| SCHEMBL13537404 | 0.75 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| Aspirin SCHEMBL1331740 | 0.75 | KDM4E (1.00) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| Aspirin SCHEMBL7580 | 0.75 | KDM4E (1.00) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| Aspirin SCHEMBL10456693 | 0.75 | KDM4E (1.00) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| Aspirin SCHEMBL29350479 | 0.75 | KDM4E (1.00) | PTGS2KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219886-A1 | NOVEL SELENO-NSAID ANALOGS AND USES THEREOF | THE PENN STATE RESEARCH FOUNDATION | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219886-A1 | NOVEL SELENO-NSAID ANALOGS AND USES THEREOF | SELENOI, SCLY, GPX1 | PTGS2 14/4885KDM4E 4047/4885HSD17B10 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.