Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876413 | 0.78 | ALDH1A1 (0.30) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25837150 | 0.78 | MAPT (0.43) | CDK1CCNB1GSK3BCDK5CDK5R1 | |
| SCHEMBL25837151 | 0.76 | MAPT (0.41) | CDK1CCNB1GSK3BCDK5CDK5R1 | |
| SCHEMBL17736806 | 0.73 | MAPT (0.43) | CDK1CCNB1GSK3BCDK5CDK5R1 | |
| SCHEMBL17736807 | 0.72 | MAPT (0.42) | CDK1CCNB1GSK3BCDK5CDK5R1 | |
| SCHEMBL25837260 | 0.72 | CDK5 (0.40) | CDK1CCNB1GSK3BCDK5CDK5R1 | |
| SCHEMBL17736805 | 0.71 | MCL1 (0.47) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL22163293 | 0.68 | MAPT (0.53) | GAAMAPTALDH1A1KMT2A | |
| SCHEMBL25837162 | 0.67 | MAPT (0.39) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL14453588 | 0.66 | MRGPRX4 (0.50) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |