SCHEMBL25837186

SCHEMBL25837186

CN(CCCOCCCNC(=O)C1(C)CC1)CCCOCCCNC(=O)C1(C)CC1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
EPHX2 P34913 2/20 0.34
ACHE P22303 1/20 0.34
CHRM2 P08172 1/20 0.33
POLB P06746 1/20 0.33
SPHK1 Q9NYA1 5/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
LTA4H P09960 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25817180 0.94 ACHE (0.39) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25816704 0.87 CHRM2 (0.39) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25816682 0.85 HPGD (0.44) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25816575 0.84 CHRM2 (0.42) CYP3A4CYP2C19SMN1; SMN2EPHX2ACHE
SCHEMBL25817158 0.84 CYP3A4 (0.34) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25816839 0.84 HPGD (0.43) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817168 0.84 HPGD (0.47) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817185 0.80 CYP3A4 (0.37) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25817012 0.73 SMN1; SMN2 (0.42) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA
SCHEMBL25837121 0.73 CYP3A4 (0.43) CYP3A4CYP2C19HPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125806-A1 CONJUGATE FOR PREVENTING AND TREATING VIRAL INFECTIONS AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2023-07-06 WO disclosed