Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 8/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545579 | 0.83 | RAB9A (0.55) | QPCTQPCTLRAB9ANPC1MAPT | |
| SCHEMBL2547500 | 0.76 | EPHX1 (0.47) | CYP1A2CYP2C19CYP3A4CYP2D6EPHX1 | |
| SCHEMBL2541353 | 0.74 | QPCT (0.54) | QPCTQPCTLPIK3CD | |
| SCHEMBL20011724 | 0.73 | EPHX1 (0.43) | QPCTMAPTEPHX1RECQL | |
| SCHEMBL1976000 | 0.71 | QPCT (0.45) | QPCTQPCTLMAPTHPGDRECQL | |
| SCHEMBL2539456 | 0.71 | QPCT (0.74) | QPCTQPCTLMAPTCDC7DBF4 | |
| SCHEMBL18126690 | 0.70 | MMP12 (0.41) | QPCTMAPTEPHX1RECQL | |
| SCHEMBL8733538 | 0.70 | QPCT (0.44) | QPCTQPCTLMAPTHPGDRECQL | |
| SCHEMBL9224383 | 0.69 | HTR1A (0.48) | QPCTRAB9AMAPTCYP3A4EPHX1 | |
| SCHEMBL2538614 | 0.69 | NPC1 (0.56) | QPCTRAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560953-A2 | NOVEL INHIBITORS | Probiodrug AG (DE) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011131748-A2 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2011-10-27 | — | — | WO | disclosed |