Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.38 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900743 | 0.84 | RPS6KA5 (0.38) | RPS6KA5RPS6KA4NOS1MEN1ALDH1A1 | |
| SCHEMBL22901013 | 0.78 | RPS6KA5 (0.32) | RPS6KA5RPS6KA4NOS1 | |
| SCHEMBL10160988 | 0.78 | GRM5 (0.33) | GRM5GRM1 | |
| SCHEMBL25837852 | 0.73 | — | — | |
| SCHEMBL25837854 | 0.73 | CA1 (0.39) | L3MBTL1 | |
| SCHEMBL22900755 | 0.72 | RPS6KA5 (0.38) | RPS6KA5RPS6KA4MEN1ALDH1A1MAPT | |
| SCHEMBL22185880 | 0.70 | MAP4K4 (0.42) | MAPT | |
| SCHEMBL22185837 | 0.70 | POLB (0.50) | MAPTL3MBTL1 | |
| SCHEMBL22185259 | 0.69 | CPB1 (0.33) | ALDH1A1KMT2AGRM5GRM1 | |
| SCHEMBL7593026 | 0.69 | ALDH1A1 (0.60) | RPS6KA5RPS6KA4MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691967-B2 | Antibiotics effective for gram-negative pathogens | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691967-B2 | Antibiotics effective for gram-negative pathogens | PGLS, MGAM, GMDS | RPS6KA5 463/4885RPS6KA4 239/4885NOS1 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.