Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837964 | 0.90 | PDK2 (0.42) | — | |
| SCHEMBL25837961 | 0.81 | PROKR1 (0.38) | — | |
| SCHEMBL25838460 | 0.80 | PDK2 (0.39) | — | |
| SCHEMBL25837986 | 0.80 | PDK2 (0.39) | — | |
| SCHEMBL25838302 | 0.80 | MEN1 (0.32) | HSD17B10 | |
| SCHEMBL25838498 | 0.79 | DPP4 (0.33) | RIPK1PRMT5WDR77HDAC8HDAC6 | |
| SCHEMBL25838462 | 0.79 | RAB9A (0.49) | NAMPT | |
| SCHEMBL30068576 | 0.78 | MAP3K12 (0.41) | — | |
| SCHEMBL25837739 | 0.78 | DPP4 (0.31) | PRMT5WDR77 | |
| SCHEMBL25838463 | 0.77 | RIPK1 (0.34) | NAMPTRIPK1HDAC8HDAC6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |