SCHEMBL25838282

SCHEMBL25838282

Cc1cc2c(c([C@@H]3CCCN3)c1)CN(c1cnn(C)c1)CC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25838280 0.92 CREBBP (0.32) HSD17B10
SCHEMBL25838493 0.85 CHRNB2 (0.33) HSD17B10
SCHEMBL25855739 0.80 PIK3CG (0.38)
SCHEMBL25838310 0.78 MEN1 (0.35)
SCHEMBL25838311 0.77 CHRM4 (0.35)
SCHEMBL25837978 0.74 HSD17B10 (0.33) HSD17B10
SCHEMBL25838309 0.72 TAAR1 (0.30)
SCHEMBL25837874 0.72 HSD17B10 (0.34) HSD17B10
SCHEMBL25838291 0.71 HSP90AA1 (0.33)
SCHEMBL30491458 0.70 EED (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131122-A1 FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2023-07-13 WO disclosed