Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983956 | 0.82 | CA12 (0.33) | CA12CA1CA2CA14CTSS | |
| SCHEMBL25838348 | 0.78 | MEN1 (0.36) | CA1CA2CTSKHDAC6 | |
| SCHEMBL22539779 | 0.76 | CA14 (0.33) | CA14HDAC6 | |
| SCHEMBL25165313 | 0.75 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL2720340 | 0.75 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL21930318 | 0.75 | L3MBTL1 (0.31) | HDAC6 | |
| SCHEMBL21930316 | 0.75 | L3MBTL1 (0.31) | HDAC6 | |
| SCHEMBL18858435 | 0.75 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL25166598 | 0.74 | — | — | |
| SCHEMBL25165441 | 0.74 | HDAC6 (0.33) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |