Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25124155 | 0.87 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL25165441 | 0.84 | HDAC6 (0.33) | HDAC6MEN1KMT2A | |
| SCHEMBL25166167 | 0.83 | USP2 (0.30) | — | |
| SCHEMBL25838348 | 0.82 | MEN1 (0.36) | HDAC6MEN1KMT2A | |
| SCHEMBL25165313 | 0.80 | HDAC6 (0.33) | HDAC6MEN1KMT2A | |
| SCHEMBL10634002 | 0.78 | L3MBTL1 (0.32) | HDAC6MEN1KMT2A | |
| SCHEMBL21403608 | 0.78 | L3MBTL1 (0.32) | HDAC6MEN1KMT2A | |
| SCHEMBL6935567 | 0.78 | L3MBTL1 (0.32) | HDAC6MEN1KMT2A | |
| SCHEMBL21403646 | 0.77 | HDAC6 (0.31) | HDAC6MEN1KMT2A | |
| SCHEMBL22539779 | 0.77 | CA14 (0.33) | HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459944-B1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2021-01-06 | — | — | EP | disclosed |
| EP-3459944-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | Merck Patent GmbH (DE) | 2019-03-27 | — | — | EP | disclosed |
| US-9994577-B2 | Azepanyl-derivatives and pharmaceutical compositions comprising the same with antiparasitic activity | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9994577-B2 | Azepanyl-derivatives and pharmaceutical compositions comprising the same with antiparasitic activity | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20170137428-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170137428-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137428-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | ACHE, PARK7, CYP51A1 | HDAC6 801/4885MEN1 343/4885KMT2A 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.