Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.47 |
| ▸ | SGK1 | O00141 | 4/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839064 | 0.79 | DYRK1A (0.56) | MAP3K11CAMKK2SGK1DYRK1ACLK1 | |
| SCHEMBL21592594 | 0.78 | MAP4K1 (0.63) | MAP3K11MAP4K1DYRK1ACLK1TNIK | |
| SCHEMBL25839031 | 0.78 | JAK2 (0.42) | MAP3K11MAP4K1CAMKK2DYRK1ACLK1 | |
| SCHEMBL8941903 | 0.74 | SGK1 (0.77) | MAP4K1CAMKK2SGK1DYRK1AABL1 | |
| SCHEMBL22922400 | 0.73 | DYRK1A (0.60) | MAP3K11MAP4K1CAMKK2SGK1DYRK1A | |
| SCHEMBL25785930 | 0.73 | AXL (0.71) | CAMKK2SGK1DYRK1AAXLTNIK | |
| SCHEMBL8320557 | 0.72 | MAPK8 (0.70) | MAP3K11MAP4K1CAMKK2SGK1DYRK1A | |
| SCHEMBL7872383 | 0.72 | TDP1 (0.44) | DYRK1A | |
| SCHEMBL17952128 | 0.72 | NTRK1 (0.62) | DYRK1AAXLTNIKMAPK8KIT | |
| SCHEMBL25839063 | 0.71 | DYRK1A (0.63) | DYRK1ACLK1DYRK1BAXLTNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |