Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.56 |
| ▸ | CLK1 | P49759 | 2/20 | 0.56 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.56 |
| ▸ | TDO2 | P48775 | 1/20 | 0.56 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 3/20 | 0.52 |
| ▸ | AXL | P30530 | 2/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.49 |
| ▸ | SGK1 | O00141 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150766 | 0.85 | DYRK1A (0.65) | DYRK1ACLK1DYRK2DYRK1BTDO2 | |
| SCHEMBL13949596 | 0.85 | DYRK1A (0.65) | DYRK1ACLK1DYRK2DYRK1BTDO2 | |
| SCHEMBL25839063 | 0.82 | DYRK1A (0.63) | DYRK1ACLK1DYRK1BKITAXL | |
| SCHEMBL25785930 | 0.81 | AXL (0.71) | DYRK1AAXLCDK8TNIKCAMKK2 | |
| SCHEMBL26174544 | 0.80 | CAMKK2 (0.61) | DYRK1ADYRK1BTDO2MAPK1CAMKK2 | |
| SCHEMBL17952128 | 0.80 | NTRK1 (0.62) | DYRK1AKITAXLCDK8TNIK | |
| SCHEMBL25838965 | 0.79 | MAP3K11 (0.52) | DYRK1ACLK1DYRK2DYRK1BMAP3K11 | |
| SCHEMBL16990255 | 0.79 | TDO2 (0.63) | DYRK1ATDO2MAPK1 | |
| SCHEMBL26174763 | 0.78 | KIT (0.49) | DYRK1ACLK1DYRK2DYRK1BMAP3K11 | |
| SCHEMBL20319257 | 0.77 | DYRK1A (0.50) | DYRK1ACLK1DYRK1BMAP3K11KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |