Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178695 | 0.78 | HPGD (0.38) | HPGDALDH1A1POLBMAPTNPC1 | |
| SCHEMBL17813461 | 0.77 | BRPF1 (0.42) | POLBMAPTBRPF1CYP1A2SMN1; SMN2 | |
| SCHEMBL1149955 | 0.76 | HPGD (0.47) | HPGDOPRK1PDE4DALDH1A1POLB | |
| SCHEMBL25839033 | 0.72 | ALOX5 (0.37) | HPGDALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL19908483 | 0.70 | ALK (0.51) | POLBMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14387485 | 0.69 | KMT2A (0.39) | POLBMAPTLMNAMEN1KMT2A | |
| SCHEMBL1979214 | 0.69 | MEN1 (0.50) | HPGDALDH1A1POLBPKMNPSR1 | |
| SCHEMBL5906514 | 0.68 | BRPF1 (0.59) | HPGDOPRK1ALDH1A1POLBPKM | |
| SCHEMBL19908258 | 0.66 | ALK (0.43) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL11884738 | 0.66 | MEN1 (0.54) | HPGDALDH1A1MAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |