Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145168 | 0.89 | NR1H2 (0.51) | NR1H2NR1H3CNR2CNR1TSHR | |
| SCHEMBL11881187 | 0.86 | NR1H2 (0.62) | NR1H2NR1H3CNR2TSHRALDH1A1 | |
| SCHEMBL10444689 | 0.82 | TAAR1 (0.50) | ALDH1A1KDM4ESMN1; SMN2AOC3 | |
| SCHEMBL9626886 | 0.82 | NR1H2 (0.49) | NR1H2NR1H3CNR2TSHRALDH1A1 | |
| SCHEMBL9626369 | 0.82 | NR1H2 (0.49) | NR1H2NR1H3CNR2TSHRALDH1A1 | |
| SCHEMBL642317 | 0.82 | CRHBP (0.61) | NR1H2NR1H3TSHRALDH1A1CRHBP | |
| SCHEMBL20227118 | 0.81 | NR1H2 (0.40) | NR1H2NR1H3CNR2CNR1MEN1 | |
| SCHEMBL8263076 | 0.81 | NR1H2 (0.54) | NR1H2NR1H3CNR2CNR1TSHR | |
| SCHEMBL6606938 | 0.81 | NR1H2 (0.54) | NR1H2NR1H3CNR2TSHRALDH1A1 | |
| SCHEMBL16980545 | 0.81 | PYCR1 (0.61) | CNR2CNR1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350180-A | Industrial preparation method and application of high-purity alpha-aminonitrile | 哈尔滨理工大学 | 2025-01-24 | — | — | CN | claimed |
| CN-119350180-A | Industrial preparation method and application of high-purity alpha-aminonitrile | 哈尔滨理工大学 | 2025-01-24 | — | — | CN | disclosed |
| US-11697648-B2 | Fused pyrimidine pyridinone compounds as JAK inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-07-11 | — | — | US | disclosed |
| US-11697648-B2 | Fused pyrimidine pyridinone compounds as JAK inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697648-B2 | Fused pyrimidine pyridinone compounds as JAK inhibitors | JAK3, JAK1, JAK2 | NR1H2 4690/4885NR1H3 4742/4885CNR2 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.