Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SPR | P35270 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24098107 | 0.81 | TSHR (0.50) | TSHRSPRKDM4EHPGDFAAH | |
| SCHEMBL15701340 | 0.80 | TSHR (0.40) | TSHRSPRRECQLHPGDHSD17B10 | |
| SCHEMBL27466983 | 0.79 | TSHR (0.48) | TSHRSPRRECQLKDM4EALDH1A1 | |
| SCHEMBL22987368 | 0.79 | CA1 (0.38) | TSHRRECQLALDH1A1LMNA | |
| SCHEMBL24098148 | 0.78 | FAAH (0.50) | TSHRSPRKDM4EALDH1A1FAAH | |
| SCHEMBL22340817 | 0.78 | FAAH (0.50) | TSHRSPRKDM4EALDH1A1FAAH | |
| SCHEMBL24098147 | 0.78 | FAAH (0.50) | TSHRSPRKDM4EALDH1A1FAAH | |
| SCHEMBL2730627 | 0.77 | SPR (0.49) | TSHRSPRKDM4EHPGDHSD17B10 | |
| SCHEMBL18466189 | 0.77 | PAOX (0.36) | RECQLKDM4EALDH1A1LMNA | |
| SCHEMBL27253736 | 0.76 | TSHR (0.42) | TSHRSPRRECQLKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137026-A1 | CAMPTOTHECIN ANALOGS CONJUGATED TO A GLUTAMINE RESIDUE IN A PROTEIN, AND THEIR USE | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-20 | — | — | WO | disclosed |