Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481229 | 0.81 | BRD4 (0.46) | LMNA | |
| SCHEMBL7736890 | 0.81 | BRD4 (0.46) | LMNA | |
| SCHEMBL14877490 | 0.81 | BRD4 (0.46) | LMNA | |
| SCHEMBL24112879 | 0.80 | ALDH1A1 (0.49) | LMNAMAPTTDP1 | |
| SCHEMBL25839738 | 0.79 | SLC6A2 (0.36) | CYP1A2CYP2C19HRH3NPC1 | |
| SCHEMBL25839734 | 0.78 | KDM1A (0.38) | GAAHRH3MAPT | |
| SCHEMBL16772741 | 0.75 | MMP2 (0.40) | GAALMNANPC1 | |
| SCHEMBL12049774 | 0.74 | CYP1A2 (0.41) | GAAOPRM1OPRL1L3MBTL1CYP1A2 | |
| SCHEMBL8260386 | 0.71 | GAA (0.40) | GAAOPRM1OPRL1L3MBTL1CYP1A2 | |
| SCHEMBL25839616 | 0.70 | CYP19A1 (0.45) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |