Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877490 | 1.00 | BRD4 (0.46) | BRD4HTR1ASRD5A1DRD2DRD1 | |
| SCHEMBL13481229 | 1.00 | BRD4 (0.46) | BRD4HTR1ASRD5A1DRD2DRD1 | |
| SCHEMBL25839738 | 0.82 | SLC6A2 (0.36) | — | |
| SCHEMBL27749604 | 0.81 | DRD2 (0.50) | HTR1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL25839734 | 0.81 | KDM1A (0.38) | KDM1A | |
| SCHEMBL25839735 | 0.81 | GAA (0.38) | LMNA | |
| SCHEMBL25839739 | 0.80 | DRD2 (0.48) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL25758990 | 0.79 | BRD4 (0.42) | BRD4HTR1ASRD5A1DRD2DRD1 | |
| Ammonia Solution, Strong SCHEMBL3406155 | 0.79 | DRD2 (0.49) | HTR1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL25758993 | 0.79 | BRD4 (0.42) | BRD4HTR1ASRD5A1DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |