Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481229 | 0.80 | BRD4 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL7736890 | 0.80 | BRD4 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL14877490 | 0.80 | BRD4 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL25839738 | 0.79 | SLC6A2 (0.36) | HTR2CSLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL27321176 | 0.77 | HTR2C (0.55) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL13652039 | 0.74 | DRD1 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL24112879 | 0.72 | ALDH1A1 (0.49) | — | |
| SCHEMBL1515269 | 0.72 | HTR2C (0.74) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL15829965 | 0.71 | DRD2 (0.60) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL11619057 | 0.70 | HTR2C (0.61) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |