SCHEMBL25839820

SCHEMBL25839820

CC(C)C1CC(OCc2cccnc2)CN1C(C)C

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.52
CHRM1 P11229 3/20 0.52
CHRM3 P20309 3/20 0.52
CHRNB2 P17787 1/20 0.45
CHRNA4 P43681 1/20 0.45
OGA O60502 1/20 0.42
NAAA Q02083 1/20 0.40
HSD11B1 P28845 1/20 0.38
PIK3CD O00329 1/20 0.38
ACACB O00763 2/20 0.37
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
AOC3 Q16853 1/20 0.36
PTAFR P25105 1/20 0.36
HRH4 Q9H3N8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25839821 0.85 PKM (0.38) CHRM2CHRM1CHRM3NAAAPIK3CD
SCHEMBL14591910 0.84 CTSL (0.46) NAAA
SCHEMBL24754491 0.79 CHRNA7 (0.43) CHRM2CHRM1CHRM3CHRNB2CHRNA4
SCHEMBL25839819 0.77 DRD4 (0.39) ACACBHRH4
SCHEMBL22049077 0.73 CHRM2 (0.72) CHRM2CHRM1CHRM3CHRNB2CHRNA4
SCHEMBL25760132 0.71 CYP11B2 (0.44) PIK3CD
SCHEMBL26178400 0.71 CTSL (0.34)
SCHEMBL7593846 0.70 CHRM2 (0.85) CHRM2CHRM1CHRM3CHRNB2CHRNA4
SCHEMBL20682295 0.70 CHRM2 (0.51) CHRM2CHRM1CHRM3CHRNB2CHRNA4
SCHEMBL7553856 0.70 CHRM2 (0.71) CHRM2CHRM1CHRM3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125825-A1 ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) 2023-07-06 WO disclosed