Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KYNU | Q16719 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23485564 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL23747281 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL24021073 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL25840243 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL23011534 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL19749935 | 0.84 | MAPT (0.48) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL21657923 | 0.84 | SIRT2 (0.48) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5221940 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL21271491 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MAPTCYP2C9 | |
| SCHEMBL21271493 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALDH1A1 1863/4885MAPK1 4249/4885L3MBTL1 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.