Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435927 | 0.98 | DPP4 (0.45) | DPP4MAPTKMT2ADPP8 | |
| SCHEMBL21565035 | 0.85 | KDM4E (0.48) | DPP4MAPTKMT2ARAB9A | |
| SCHEMBL21565165 | 0.85 | DPP4 (0.53) | DPP4DPP8DPP7 | |
| SCHEMBL21985096 | 0.85 | DPP4 (0.51) | DPP4MAPTKMT2A | |
| SCHEMBL28424221 | 0.80 | DPP4 (0.40) | DPP4DPP8DPP7 | |
| SCHEMBL28424229 | 0.79 | OPRK1 (0.39) | DPP4RAB9A | |
| SCHEMBL21565049 | 0.77 | KDM4E (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL29196914 | 0.77 | DPP4 (0.55) | DPP4KMT2ADPP8DPP7 | |
| SCHEMBL24725614 | 0.76 | ATM (0.50) | DPP4KMT2AHPGDRAB9A | |
| SCHEMBL28440209 | 0.74 | ATM (0.52) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4050102-B1 | TRANSAMINASE MUTANT AND USE THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATE | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2026-03-11 | — | — | EP | claimed |
| US-20230203550-A1 | USE OF STEREOSELECTIVE TRANSAMINASE IN ASYMMETRIC SYNTHESIS OF CHIRAL AMINE | ABIOCHEM BIOTECHNOLOGY CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |