Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440209 | 0.98 | ATM (0.52) | ATMALDH1A1TRPV1L3MBTL1TDP1 | |
| SCHEMBL23272135 | 0.77 | DPP4 (0.55) | L3MBTL1KMT2ATDP1DPP4 | |
| SCHEMBL25840260 | 0.76 | DPP4 (0.44) | KMT2AHPGDRAB9ADPP4 | |
| SCHEMBL28435927 | 0.74 | DPP4 (0.45) | KMT2ADPP4 | |
| SCHEMBL8092673 | 0.74 | NPC1 (0.55) | TRPV1TDP1NPC1 | |
| SCHEMBL30427892 | 0.73 | F13A1 (0.50) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL536350 | 0.73 | F13A1 (0.50) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25840236 | 0.72 | DPP4 (0.77) | DPP4 | |
| SCHEMBL5001351 | 0.72 | NPC1 (0.57) | TDP1NPC1 | |
| SCHEMBL19574089 | 0.72 | ATM (0.95) | ATMALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396816-A1 | A TRANSAMINASE MUTANT AND APPLICATION THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATES | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2022-12-15 | — | — | US | disclosed |