Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725614 | 0.98 | ATM (0.50) | ATMALDH1A1DPP4TRPV1L3MBTL1 | |
| SCHEMBL23272135 | 0.78 | DPP4 (0.55) | DPP4L3MBTL1TDP1 | |
| SCHEMBL28435927 | 0.75 | DPP4 (0.45) | DPP4 | |
| SCHEMBL7891864 | 0.75 | DPP4 (0.67) | DPP4 | |
| SCHEMBL30427892 | 0.74 | F13A1 (0.50) | — | |
| SCHEMBL536350 | 0.74 | F13A1 (0.50) | — | |
| SCHEMBL25840260 | 0.74 | DPP4 (0.44) | DPP4 | |
| SCHEMBL5001351 | 0.73 | NPC1 (0.57) | NPC1TDP1 | |
| SCHEMBL8092673 | 0.72 | NPC1 (0.55) | TRPV1NPC1TDP1 | |
| SCHEMBL13501505 | 0.72 | DPP4 (0.40) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111534494-B | (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate | 浙江工业大学 | 2021-10-01 | — | — | CN | claimed |
| CN-111411095-B | Recombinant (R) -omega-transaminase, mutant and application thereof | 浙江工业大学 | 2021-07-23 | — | — | CN | claimed |
| CN-111534494-A | (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate | 浙江工业大学 | 2020-08-14 | — | — | CN | claimed |
| CN-111411095-A | Novel recombinant (R) -omega-transaminase, mutant and application thereof | 浙江工业大学 | 2020-07-14 | — | — | CN | claimed |
| CN-111534494-B | (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate | 浙江工业大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-111534494-B | (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate | 浙江工业大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-111411095-B | Recombinant (R) -omega-transaminase, mutant and application thereof | 浙江工业大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-111534494-A | (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate | 浙江工业大学 | 2020-08-14 | — | — | CN | disclosed |
| CN-111534494-A | (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate | 浙江工业大学 | 2020-08-14 | — | — | CN | disclosed |
| CN-111411095-A | Novel recombinant (R) -omega-transaminase, mutant and application thereof | 浙江工业大学 | 2020-07-14 | — | — | CN | disclosed |