Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258488 | 0.87 | ABAT (0.64) | SMN1; SMN2GAANPSR1ABATMEN1 | |
| SCHEMBL25840841 | 0.85 | NPC1 (0.55) | SMN1; SMN2TDP1MAPTMEN1CYP1A2 | |
| SCHEMBL23328386 | 0.85 | CDK1 (0.56) | SMN1; SMN2GAAMAPTABATMEN1 | |
| SCHEMBL10453740 | 0.83 | IDO1 (0.49) | GAAMAPKAPK2MAPTMAPK1ABAT | |
| SCHEMBL25840794 | 0.80 | ABAT (0.72) | SMN1; SMN2GAAMAPTABATMEN1 | |
| SCHEMBL1039226 | 0.80 | MAPT (0.47) | GAANPSR1TDP1MAPTMEN1 | |
| SCHEMBL21319443 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2GAANPSR1TDP1MAPT | |
| SCHEMBL12301492 | 0.75 | TDP1 (0.65) | SMN1; SMN2GAATDP1MAPTMEN1 | |
| SCHEMBL14679376 | 0.75 | POLB (0.54) | SMN1; SMN2NPSR1MAPTMEN1HTT | |
| SCHEMBL3975014 | 0.75 | MAPKAPK2 (0.57) | SMN1; SMN2GAAMAPKAPK2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701333-B2 | Antibacterial compounds | Kent Innovation & Enterprise (GB) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701333-B2 | Antibacterial compounds | ARF1, ARL1, TLR1 | SMN1; SMN2 3087/4885GAA 1854/4885NPSR1 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.