SCHEMBL25841014

SCHEMBL25841014

OP(O)CNC(=S)Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.67
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
LMNA P02545 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
HTT P42858 2/20 0.61
MAPT P10636 2/20 0.61
ALDH1A1 P00352 1/20 0.61
GAA P10253 1/20 0.61
KIF11 P52732 1/20 0.50
EPHX2 P34913 1/20 0.49
MYC P01106 1/20 0.46
MAX P61244 1/20 0.46
HPGD P15428 1/20 0.43
MTOR P42345 1/20 0.43
CXCR4 P61073 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9453957 0.82 CDK1 (0.68) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL25841058 0.81 LMNA (0.72) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL14386106 0.81 LMNA (0.72) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL25841306 0.80 EPHX2 (0.49) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL25841012 0.80 EPHX2 (0.68) MEN1KMT2AHTTMAPTKIF11
SCHEMBL14386216 0.80 CDK1 (1.00) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL25841137 0.79 CDK1 (0.65) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL23328373 0.78 ABAT (0.66) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL23328363 0.78 CDK1 (0.63) CDK1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL31276967 0.78 CDK1 (0.82) CDK1MEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11701333-B2 Antibacterial compounds Kent Innovation & Enterprise (GB) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701333-B2 Antibacterial compounds ARF1, ARL1, TLR1 CDK1 1597/4885MEN1 1300/4885KMT2A 2533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.